Protein name:
Dual oxidase 1 ;
Alternative:
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Interacts with TXNDC11, TPO and CYBA.
Function:
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Subcellular Location:
Apical cell membrane
Multi-pass membrane protein
Localizes to the apical membrane of epithelial cells.
Protein Attributes:
50:
MGFRLALAWT | LLVGPWMPMG | ARNSISWEVQ | RFDGWYNNLM | EHKWGSKGSR |
100:
LQRLVPASYA | DGVYQPLGEP | HLPNPRDLSN | TAMRGPAGQA | SLRNRTVLGV |
150:
FFGYHVLSDL | VSIEKPGCPA | EFLNIHIPPG | DPVFDPHKSG | DVVLPFQRSR |
200:
WDPNTGQSPS | NPRDLTNEVT | GWLDGSAIYG | SSHSWSDELR | SFSGGQLASG |
250:
PDPAFPRQAQ | DPLFMWTPPD | PATGQRGPQG | LYAFGAEQGN | REPFLQALGL |
300:
LWFRYHNLCA | QKLAREHPLW | GDEELFQHAR | KRVIATYQSI | TMYEWLPSFL |
350:
RKMPQEYTGY | RPFLDPSISP | EFLAASEQFF | STMVPPGVYM | RNASCHFQGV |
400:
INRNSSVSRA | LRVCNSYWSR | EHPNLQRAED | VDALLLGMAS | QIAEREDHMV |
450:
VEDVQDFWPG | PLKFSRTDHL | ASCLQRGRDL | GLPSYTKARA | RLGLPPVTRW |
500:
QDINPALSRS | DGIVLEATAA | LYNQDLSRLE | LLPGGLLESY | GDPGPLFSTI |
550:
VLDQFVRLRD | GDRYWFENTK | NGLFSEKEIA | EIRNTSLRDV | LVAVTNMTPG |
600:
ALQPNVFFWH | AGDPCPQPRQ | LSTKDLPACA | PLIMRDYFKG | SGFGFGVTIG |
650:
TLCCFPLVSL | LSAWIVAQLR | RRNFKRLQVQ | NRQSIMCEKL | VGGMKALEWQ |
700:
GRKEPCRPVL | VHLQSGQIHV | MDGRLSVLRT | IQLRPPQQVN | LILSSNHGRR |
750:
TLLLKIPKEY | DLVLMFDLEE | ERQVMVENLQ | SALKESGLSF | QEWELREQEL |
800:
MRAAVTREQR | SHLLETFFRH | LFSQVLDIDQ | ADAGALPLDS | SQKVREALTC |
850:
ELSRAEFAES | LGLKPQDMFV | ESMFSLADKD | GNGYLSFREF | LDILVVFMKG |
900:
SPEEKSRLMF | RMYDFDGNGL | ISKDEFIRML | RSFIEISNNC | LSKAQLTEVV |
950:
ESMFREAGFQ | DKQELTWEDF | HFMLRDHDSE | LRFTQLCVKG | VEVPEVIKDL |
1000:
CRRASYISQE | KLCPSPRVSA | HCPRSNVDVE | VELTPWKLQC | PTDTDPPQEI |
1050:
RRRFGKKVTS | FQPLLFTEAH | REKFQRSRRH | QTVQQFKRFV | ENYRRHIGCL |
1100:
AVFYTIAGGL | FLERAYYYAF | AAHHMGITDT | TRVGIILSRG | TAASISFMFS |
1150:
YILLTMCRNL | ITFLRETFLN | RYVPFDAAVD | FHRLIASTAI | ILTVLHSAGH |
1200:
VVNVYLFSIS | PLSVLSCLFP | GLFHDNGSEF | PQKYYWWFFQ | TVPGLTGVML |
1250:
LLILAIMYVF | ASHHFRRCSF | RGFWLTHHLY | ILLYMLLIIH | GSFALIQLPR |
1300:
FHIFFLVPAL | IYVGDKLVSL | SRKKVEISVV | KAELLPSGVT | HLQFQRPQGF |
1350:
EYKSGQWVRI | ACLALGTTEY | HPFTLTSAPH | EDTLSLHIRA | AGPWTTRLRE |
1400:
IYSPPTDDNC | AKYPKLYLDG | PFGEGHQEWH | KFEVSVLVGG | GIGVTPFASI |
1450:
LKDLVFKSSV | SCQVFCKKIY | FIWVTRTQRQ | FEWLADIIRE | VEENDHRDLV |
1500:
SVHIYITQLA | EKFDLRTTML | YICERHFQKV | LNRSLFTGLR | SITHFGRPPF |
1550:
EPFFNSLQEV | HPQVRKIGVF | SCGPPGMTKN | VEKACQLINR | QDRTHFSHHY |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Dog
Pig
ELISA Kit for Pig Dual oxidase 1
ELISA Kit for Pig Dual oxidase 1
ELISA Kit for Pig Dual oxidase 1
ELISA Kit for Pig Dual oxidase 1
CLIA Kit for Pig Dual oxidase 1
CLIA Kit for Pig Dual oxidase 1
CLIA Kit for Pig Dual oxidase 1
CLIA Kit for Pig Dual oxidase 1
Polyclonal Antibody for Pig Dual oxidase 1
Polyclonal Antibody for Pig Dual oxidase 1
Polyclonal Antibody for Pig Dual oxidase 1
Polyclonal Antibody for Pig Dual oxidase 1
Monoclonal Antibody for Pig Dual oxidase 1
Monoclonal Antibody for Pig Dual oxidase 1
Monoclonal Antibody for Pig Dual oxidase 1
Monoclonal Antibody for Pig Dual oxidase 1
Protein for Pig Dual oxidase 1
Protein for Pig Dual oxidase 1
Protein for Pig Dual oxidase 1
Protein for Pig Dual oxidase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Thyroid .
2.
"Dual oxidase2 is expressed all along the digestive tract."
Ameziane-El-Hassani R.
,
Benfares N.
,
Caillou B.
,
Talbot M.
,
Sabourin J.-C.
,
Belotte V.
,
Morand S.
,
Gnidehou S.
,
Agnandji D.
,
Ohayon R.
,
Kaniewski J.
,
Noel-Hudson M.-S.
,
Bidart J.-M.
,
Schlumberger M.
,
Virion A.
,
Dupuy C.
Am. J. Physiol.288:G933-G942(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY